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Figure 1: LOXL-2- lysyl oxidase like -2, PI3K- Phosphoinositol-3kinase (signaling pathway), Protein kinase B (Akt), mTOR - Mechanistic target of rapamycin, HIF-1- Hypoxia-inducible factor 1, TGF-β - Transforming growth factor beta, CTGF- Connective tissue growth factor, Ang II - angiotensin II, IL6 -Interleukin 6, PDGF - Platelet-derived growth factor, α SMA -Alpha-smooth muscle actin, TIMPs -Tissue inhibitors of metalloproteinases, MMPs - Matrix metalloproteinases, PINP -Serum procollagen type I N-propeptide , PICP- Procollagen Type I Carboxyterminal Propeptide, PIIINP- N-terminal propeptide of type III procollagen, MEK -Mitogen activated protein Kinase, ERK – Extracellular signal regulated kinase |
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