Figure 1: Mechanism of entry of the severe acute respiratory syndrome coronavirus 2 (created with BioRender.com). Severe acute respiratory syndrome coronavirus-2 invasion in host cells via interaction of S protein with host's angiotensin-converting enzyme 2 receptors. This causes priming of S2 by TMPRSS2 to release S2 fragment. S2 mediates fusion of virus with host cell membrane resulting in virus uptake. The virus is processed via the endocytic pathway and eventually more virions are released (Note: The image has been made using BioRender).