Journal of the Practice of Cardiovascular Sciences

SYSTEMATIC REVIEW
Year
: 2022  |  Volume : 8  |  Issue : 3  |  Page : 144--151

Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review


Punyatoya Bej1, Sambhunath Das2 
1 Associate Professor, Department of Community Medicine, Rama Medical College and Research Centre, Hapur, Uttar Pradesh, India
2 Professor, Department of Cardiac Anaesthesia, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Punyatoya Bej
Associate Professor, Department of Community Medicine, Rama Medical College and Research Centre, Hapur, Uttar Pradesh
India

Pregnancy-induced hypertension (PIH) is one of the main causes of maternal mortality. Many first- and second-line drugs are available to treat the condition. Labetalol lowers blood pressure by blocking both α and β adrenergic receptors. It preserves uteroplacental blood flow efficiently. A systemic review was carried out to find the efficacy and safety of labetalol in the treatment of PIH. Three thousand twenty-six studies were retrieved in 20 years. Finally, 28 studies were selected after applying the review criteria. Twenty-three studies detected that labetalol had superior or similar action compared to other drugs in controlling hypertension in patients with preeclampsia and eclampsia. The systematic review concluded that labetalol is a safe, effective, first-choice of drug with few side effects in treating PIH.


How to cite this article:
Bej P, Das S. Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review.J Pract Cardiovasc Sci 2022;8:144-151


How to cite this URL:
Bej P, Das S. Effect of labetalol for treating patients with pregnancy-induced hypertension: A systematic review. J Pract Cardiovasc Sci [serial online] 2022 [cited 2023 Feb 1 ];8:144-151
Available from: https://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=3;spage=144;epage=151;aulast=Bej;type=0