Journal of the Practice of Cardiovascular Sciences

ORIGINAL ARTICLE
Year
: 2022  |  Volume : 8  |  Issue : 2  |  Page : 84--89

Evaluation of systolic time intervals in patients of ischemic heart disease with clinical heart failure


Smitha Pernaje Seetharam1, MS Vinutha Shankar1, Niranjan Reddy2 
1 Department of Physiology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India
2 Department of Cardiology, R. L. Jalappa Narayana Heart Centre, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India

Correspondence Address:
Smitha Pernaje Seetharam
Department of Physiology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar - 563 103, Karnataka
India

Introduction: Left ventricular (LV) systolic function evaluation is based on ejection fraction assessment. Due to the great sensitivity of the examination and the ease of measurement, systolic time intervals (STIs) are ideally appropriate for studying the effects of pharmacologic agents upon the heart. In this context, the present study aimed to estimate and compare STI in patients with ischemic heart disease (IHD) with clinical heart failure and among control subjects without clinically established LV dysfunction based on their LV ejection fraction (LVEF). Materials and Methods: This case–control study included 33 IHD patients as cases and 32 healthy subjects as controls. All subjects underwent pulsed-Doppler echocardiogram to estimate STIs: total electromechanical systole (QS2), preejection period (PEP), and LV ejection time (LVET). Results: A significant difference between PEP (145.23 ± 23.20 vs. 82.99 ± 8.63, P < 0.00001), LVET (231.34 ± 40.89 vs. 265.39 ± 31.98, P = 0.000947), and PEP/LVET ratio (0.63 ± 0.15 vs. 0.31 ± 0.08, P < 0.00001) between cases and controls was found. On subgroup analysis, a weak correlation was found in patients with LVEF ≤40% and PEP/LVET (r = −0.3677, P = 0.1958). In addition, a relatively strong correlation between LVET and heart rate (r = −0.432, P = 0.012) was found among the cases. Conclusion: The current study results showed that the differences in the values of STI among cases than in controls could be an indicator of LV systolic dysfunction. In addition, this method may have impending applications in the management of IHD.


How to cite this article:
Seetharam SP, Vinutha Shankar M S, Reddy N. Evaluation of systolic time intervals in patients of ischemic heart disease with clinical heart failure.J Pract Cardiovasc Sci 2022;8:84-89


How to cite this URL:
Seetharam SP, Vinutha Shankar M S, Reddy N. Evaluation of systolic time intervals in patients of ischemic heart disease with clinical heart failure. J Pract Cardiovasc Sci [serial online] 2022 [cited 2022 Sep 26 ];8:84-89
Available from: https://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=2;spage=84;epage=89;aulast=Seetharam;type=0