ORIGINAL ARTICLE
Year : 2017 | Volume
: 3 | Issue : 3 | Page : 143--149
Epidemiology of cardiomyopathy – A Clinical and Genetic Study of Restrictive Cardiomyopathy: The EPOCH-R Study
Mitali Kapoor1, Soumi Das1, Amitabh Biswas1, Sandeep Seth2, Balram Bhargava2, Vadlamudi Raghavendra Rao1
1 Department of Anthropology, University of Delhi, New Delhi, India
2 Department of Cardiology, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Prof. Vadlamudi Raghavendra Rao
Department of Anthropology, Laboratory of Biochemical and Molecular Anthropology, University of Delhi, New Delhi - 110 007
India
Introduction: Restrictive cardiomyopathy (RCM) is characterized by diastolic dysfunction, biatrial enlargement, and normal or near-normal systolic function. RCM is the rarest kind among cardiomyopathies with a severe outcome. Methods: Here, we present the clinical outcomes of thirty RCM patients recruited from a tertiary care unit of India, All India Institute of Medical Sciences, New Delhi. For clinical assessment, patients underwent electrocardiogram, echocardiography, and cardiac catheterization, and endomyocardial biopsy whenever required. Results: Out of 190 patients with cardiomyopathy, 100 had dilated cardiomyopathy, 60 had hypertrophic cardiomyopathy, and 30 had idiopathic RCM and were recruited for the study. Out of these thirty patients, 63.3% were males. A maximum number of patients were diagnosed in their second to third decade of life. Atrial fibrillation (73.3%) and ST-T abnormalities (76.6%) were common. Most of the patients showed the early age of onset with symptoms emerging in the first and second decades of life. Shortness of breath and fatigue were found to be common symptoms. No familial cases were found. Conclusion: RCM in India is a sporadic disease, rare, and occurs in the young. Prognosis of RCM is still worse than any other cardiomyopathy.
How to cite this article:
Kapoor M, Das S, Biswas A, Seth S, Bhargava B, Rao VR. Epidemiology of cardiomyopathy – A Clinical and Genetic Study of Restrictive Cardiomyopathy: The EPOCH-R Study.J Pract Cardiovasc Sci 2017;3:143-149
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How to cite this URL:
Kapoor M, Das S, Biswas A, Seth S, Bhargava B, Rao VR. Epidemiology of cardiomyopathy – A Clinical and Genetic Study of Restrictive Cardiomyopathy: The EPOCH-R Study. J Pract Cardiovasc Sci [serial online] 2017 [cited 2023 Jun 4 ];3:143-149
Available from: https://www.j-pcs.org/article.asp?issn=2395-5414;year=2017;volume=3;issue=3;spage=143;epage=149;aulast=Kapoor;type=0 |
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